Background-suppressed live visualization of genomic loci with an improved CRISPR system based on a split fluorophore

The higher-order structural organization and dynamics of the chromosomes play a central role in gene regulation. To explore this structure–function relationship, it is necessary to directly visualize genomic elements in living cells. Genome imaging based on the CRISPR system is a powerful approach b...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhary, Narendra, Nho, Si-Hyeong, Cho, Hayoon, Gantumur, Narangerel, Ra, Jae Sun, Myung, Kyungjae, Kim, Hajin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545142/
https://www.ncbi.nlm.nih.gov/pubmed/32887690
http://dx.doi.org/10.1101/gr.260018.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545142/
https://www.ncbi.nlm.nih.gov/pubmed/32887690
http://dx.doi.org/10.1101/gr.260018.119

Ejemplares similares