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Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms
Eukaryotic genes often generate a variety of RNA isoforms that can lead to functionally distinct protein variants. The synthesis and stability of RNA isoforms is poorly characterized because current methods to quantify RNA metabolism use short-read sequencing and cannot detect RNA isoforms. Here we...
Autores principales: | Maier, Kerstin C., Gressel, Saskia, Cramer, Patrick, Schwalb, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545145/ https://www.ncbi.nlm.nih.gov/pubmed/32887688 http://dx.doi.org/10.1101/gr.257857.119 |
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