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Molecular barcoding of native RNAs using nanopore sequencing and deep learning

Nanopore sequencing enables direct measurement of RNA molecules without conversion to cDNA, thus opening the gates to a new era for RNA biology. However, the lack of molecular barcoding of direct RNA nanopore sequencing data sets severely affects the applicability of this technology to biological sa...

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Detalles Bibliográficos
Autores principales: Smith, Martin A., Ersavas, Tansel, Ferguson, James M., Liu, Huanle, Lucas, Morghan C., Begik, Oguzhan, Bojarski, Lilly, Barton, Kirston, Novoa, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545146/
https://www.ncbi.nlm.nih.gov/pubmed/32907883
http://dx.doi.org/10.1101/gr.260836.120