Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing

Improved identification of structural variants (SVs) in cancer can lead to more targeted and effective treatment options as well as advance our basic understanding of the disease and its progression. We performed whole-genome sequencing of the SKBR3 breast cancer cell line and patient-derived tumor...

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Detalles Bibliográficos
Autores principales: Aganezov, Sergey, Goodwin, Sara, Sherman, Rachel M., Sedlazeck, Fritz J., Arun, Gayatri, Bhatia, Sonam, Lee, Isac, Kirsche, Melanie, Wappel, Robert, Kramer, Melissa, Kostroff, Karen, Spector, David L., Timp, Winston, McCombie, W. Richard, Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545150/
https://www.ncbi.nlm.nih.gov/pubmed/32887686
http://dx.doi.org/10.1101/gr.260497.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545150/
https://www.ncbi.nlm.nih.gov/pubmed/32887686
http://dx.doi.org/10.1101/gr.260497.119

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