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Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Post-inflammatory behaviours in rodents are widely used to model human depression and to test the efficacy of novel anti-depressants. Mice injected with lipopolysaccharide (LPS) display a depressive-like phenotype twenty-four hours after endotoxin administration. Despite the widespread use of this m...

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Detalles Bibliográficos
Autores principales: Chan, Shi Yu, Probert, Fay, Radford-Smith, Daniel E., Hebert, Jennifer C., Claridge, Timothy D. W., Anthony, Daniel C., Burnet, Philip W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545201/
https://www.ncbi.nlm.nih.gov/pubmed/33033375
http://dx.doi.org/10.1038/s41598-020-74008-w