JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

The interplay between the Yamanaka factors (OCT4, SOX2, KLF4 and c-MYC) and transcriptional/epigenetic co-regulators in somatic cell reprogramming is incompletely understood. Here, we demonstrate that the histone H3 lysine 27 trimethylation (H3K27me3) demethylase JMJD3 plays conflicting roles in mou...

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Detalles Bibliográficos
Autores principales: Huang, Yinghua, Zhang, Hui, Wang, Lulu, Tang, Chuanqing, Qin, Xiaogan, Wu, Xinyu, Pan, Meifang, Tang, Yujia, Yang, Zhongzhou, Babarinde, Isaac A., Lin, Runxia, Ji, Guanyu, Lai, Yiwei, Xu, Xueting, Su, Jianbin, Wen, Xue, Satoh, Takashi, Ahmed, Tanveer, Malik, Vikas, Ward, Carl, Volpe, Giacomo, Guo, Lin, Chen, Jinlong, Sun, Li, Li, Yingying, Huang, Xiaofen, Bao, Xichen, Gao, Fei, Liu, Baohua, Zheng, Hui, Jauch, Ralf, Lai, Liangxue, Pan, Guangjin, Chen, Jiekai, Testa, Giuseppe, Akira, Shizuo, Hu, Jifan, Pei, Duanqing, Hutchins, Andrew P., Esteban, Miguel A., Qin, Baoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545202/
https://www.ncbi.nlm.nih.gov/pubmed/33033262
http://dx.doi.org/10.1038/s41467-020-18900-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545202/
https://www.ncbi.nlm.nih.gov/pubmed/33033262
http://dx.doi.org/10.1038/s41467-020-18900-z

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