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Targeted delivery of 5-fluorouracil-1-acetic acid (5-FA) to cancer cells overexpressing epithelial growth factor receptor (EGFR) using virus-like nanoparticles

Chemotherapy is widely used in cancer treatments. However, non-specific distribution of chemotherapeutic agents to healthy tissues and normal cells in the human body always leads to adverse side effects and disappointing therapeutic outcomes. Therefore, the main aim of this study was to develop a ta...

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Detalles Bibliográficos
Autores principales: Gan, Bee Koon, Rullah, Kamal, Yong, Chean Yeah, Ho, Kok Lian, Omar, Abdul Rahman, Alitheen, Noorjahan Banu, Tan, Wen Siang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545207/
https://www.ncbi.nlm.nih.gov/pubmed/33033330
http://dx.doi.org/10.1038/s41598-020-73967-4