Protection against herpes simplex virus type 2 infection in a neonatal murine model using a trivalent nucleoside-modified mRNA in lipid nanoparticle vaccine

Neonatal herpes is a dreaded complication of genital herpes infection in pregnancy. We recently compared two vaccine platforms for preventing genital herpes in female mice and guinea pigs and determined that HSV-2 glycoproteins C, D and E expressed using nucleoside-modified mRNA in lipid nanoparticl...

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Detalles Bibliográficos
Autores principales: LaTourette, Philip C., Awasthi, Sita, Desmond, Angela, Pardi, Norbert, Cohen, Gary H., Weissman, Drew, Friedman, Harvey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545304/
https://www.ncbi.nlm.nih.gov/pubmed/33041105
http://dx.doi.org/10.1016/j.vaccine.2020.09.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545304/
https://www.ncbi.nlm.nih.gov/pubmed/33041105
http://dx.doi.org/10.1016/j.vaccine.2020.09.079

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