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GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds

With disease-modifying compounds targeting alpha-synuclein available in clinical trials, patient stratification according to alpha-synuclein-specific enrichment strategies is a much-needed prerequisite. Such a scenario will be exemplified for GBA, one major genetic risk factor that is specifically a...

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Detalles Bibliográficos
Autor principal: Brockmann, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545538/
https://www.ncbi.nlm.nih.gov/pubmed/33102473
http://dx.doi.org/10.3389/fcell.2020.562522