Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients

OBJECTIVE: Reduction in glucocerebrosidase (GCase; encoded by GBA) enzymatic activity has been linked to Parkinson’s disease (PD). Here, we correlated GCase activity and PD phenotype in the Parkinson’s Progression Markers Initiative (PPMI) cohort. METHODS: We measured GCase activity in dried blood s...

Descripción completa

Detalles Bibliográficos
Autores principales: Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, Caspell‐Garcia, Chelsea, Blauwendraat, Cornelis, Foroud, Tatiana, Nudelman, Kelly, Gan‐Or, Ziv, Simuni, Tanya, Chahine, Lana M., Levy, Oren, Zheng, Dandi, Li, Gen, Sardi, Sergio Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545591/
https://www.ncbi.nlm.nih.gov/pubmed/32888397
http://dx.doi.org/10.1002/acn3.51164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545591/
https://www.ncbi.nlm.nih.gov/pubmed/32888397
http://dx.doi.org/10.1002/acn3.51164

Ejemplares similares