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Loss of ACSM3 confers worsened prognosis and immune exclusion to cutaneous melanoma

Aim: Malignant melanoma (MM) is a highly aggressive cutaneous cancer with undetermined underlying genetic disposition. We aim to evaluate prognostic and mechanistic role of ACSM3 in MM. Methods: In silico reproduction of TCGA MM dataset, GEO dataset, GDSC dataset and human protein atlas was performe...

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Detalles Bibliográficos
Autores principales: Zhu, Zhidong, Wang, Duoqin, Shen, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545663/
https://www.ncbi.nlm.nih.gov/pubmed/33046979
http://dx.doi.org/10.7150/jca.48354