Cargando…

Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma

Arsenic trioxide (ATO) is widely studied for its antitumor efficacy and several recent studies suggested the immune modulatory effects of ATO in animal models. In this study we found ATO treatment induced increased ROS production and DNA damage in esophageal squamous cell carcinoma (ESCC) cells, led...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Guanxia, Li, Xia, Li, Jiong, Zhou, Wei, Chen, Zhongjian, Fan, Yun, Jiang, Youhua, Zhao, Yue, Sun, Guogui, Mao, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545676/
https://www.ncbi.nlm.nih.gov/pubmed/33046973
http://dx.doi.org/10.7150/jca.47111