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YAP increases response to Trastuzumab in HER2-positive Breast Cancer by enhancing P73-induced apoptosis

The role of the Yes-associated protein (YAP) in oncogenesis and progression of breast cancer remains controversial. Meanwhile, development of therapeutic resistance to trastuzumab, a common breast cancer treatment administered after chemotherapy, is a significant challenge in the treatment of HER2-p...

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Detalles Bibliográficos
Autores principales: Cao, Lanqing, Yao, Min, Sasano, Hironobu, Sun, Ping-Li, Gao, Hongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545685/
https://www.ncbi.nlm.nih.gov/pubmed/33046997
http://dx.doi.org/10.7150/jca.48535