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Mycobacterium tuberculosis-specific plasmablast levels are differentially modulated in tuberculosis infection and disease

BACKGROUND: While T cell responses to Mycobacterium tuberculosis (Mtb) have been extensively studied, the role of B-cells and antibodies are less well characterised. The aim of this study was to assess levels of Mtb-specific IgG + plasmablasts across the Mtb infection spectrum. METHODS: Patients wit...

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Detalles Bibliográficos
Autores principales: Gindeh, Awa, Owolabi, Olumuyiwa, Donkor, Simon, Sutherland, Jayne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545693/
https://www.ncbi.nlm.nih.gov/pubmed/32781412
http://dx.doi.org/10.1016/j.tube.2020.101978