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Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos

Well-orchestrated epigenetic modifications during early development are essential for embryonic survival and postnatal growth. Erroneous epigenetic modifications due to environmental perturbations such as manipulation and culture of embryos during in vitro fertilization (IVF) are linked to various s...

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Detalles Bibliográficos
Autores principales: Fu, Wei, Yue, Yuan, Miao, Kai, Xi, Guangyin, Zhang, Chao, Wang, Wenjuan, An, Lei, Tian, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545699/
https://www.ncbi.nlm.nih.gov/pubmed/33061820
http://dx.doi.org/10.7150/ijbs.51607