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Deletion of Mitochondrial Uncoupling Protein 2 Exacerbates Mitochondrial Damage in Mice Subjected to Cerebral Ischemia and Reperfusion Injury under both Normo- and Hyperglycemic Conditions

Deletion of mitochondrial uncoupling protein 2 (UCP2) has been shown to aggravate ischemic damage in the brain. However, the underlying mechanisms are not fully understood. The objective of this study is to explore the impact of homozygous UCP2 deletion (UCP2(-/-)) on mitochondrial fission and fusio...

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Detalles Bibliográficos
Autores principales: He, Maotao, Ma, Yanmei, Wang, Rui, Zhang, Jianzhong, Jing, Li, Li, P. Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545711/
https://www.ncbi.nlm.nih.gov/pubmed/33061796
http://dx.doi.org/10.7150/ijbs.48204