Cargando…
Deletion of Mitochondrial Uncoupling Protein 2 Exacerbates Mitochondrial Damage in Mice Subjected to Cerebral Ischemia and Reperfusion Injury under both Normo- and Hyperglycemic Conditions
Deletion of mitochondrial uncoupling protein 2 (UCP2) has been shown to aggravate ischemic damage in the brain. However, the underlying mechanisms are not fully understood. The objective of this study is to explore the impact of homozygous UCP2 deletion (UCP2(-/-)) on mitochondrial fission and fusio...
Autores principales: | He, Maotao, Ma, Yanmei, Wang, Rui, Zhang, Jianzhong, Jing, Li, Li, P. Andy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545711/ https://www.ncbi.nlm.nih.gov/pubmed/33061796 http://dx.doi.org/10.7150/ijbs.48204 |
Ejemplares similares
-
Deletion of mitochondrial uncoupling protein 2 exacerbates mitophagy and cell apoptosis after cerebral ischemia and reperfusion injury in mice
por: He, Maotao, et al.
Publicado: (2020) -
Targeted activation of ERK1/2 reduces ischemia and reperfusion injury in hyperglycemic myocardium by improving mitochondrial function
por: Yu, Fei, et al.
Publicado: (2022) -
Inhibition of ALDH2 by O-GlcNAcylation contributes to the hyperglycemic exacerbation of myocardial ischemia/reperfusion injury
por: Liu, Baoshan, et al.
Publicado: (2016) -
Glucocorticoids Suppress Mitochondrial Oxidant Production via Upregulation of Uncoupling Protein 2 in Hyperglycemic Endothelial Cells
por: Gerö, Domokos, et al.
Publicado: (2016) -
Aging Exacerbates Ischemia-Reperfusion-Induced Mitochondrial Respiration Impairment in Skeletal Muscle
por: Paradis, Stéphanie, et al.
Publicado: (2019)