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Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway

BACKGROUND: The X-linked gene WTX (also called AMER1) has been reported to function as a tumour suppressor gene in Wilms’ tumour. In our previous study, WTX expression was shown to be significantly reduced in gastric cancer (GC), but the function and mechanism associated with WTX loss had yet to be...

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Detalles Bibliográficos
Autores principales: Li, Jian, Ye, Danli, Shen, Peng, Liu, Xiaorong, Zhou, Peirong, Zhu, Guifang, Xu, Yangwei, Fu, Yun, Li, Xuanqi, Sun, Jingbo, Xu, Jia, Zhang, Qingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545863/
https://www.ncbi.nlm.nih.gov/pubmed/33032635
http://dx.doi.org/10.1186/s13046-020-01718-4