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Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice

Neuropsychological deficits, including impairments in learning and memory, occur after spinal cord injury (SCI). In experimental SCI models, we and others have reported that such changes reflect sustained microglia activation in the brain that is associated with progressive neurodegeneration. In the...

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Detalles Bibliográficos
Autores principales: Li, Yun, Ritzel, Rodney M., Khan, Niaz, Cao, Tuoxin, He, Junyun, Lei, Zhuofan, Matyas, Jessica J., Sabirzhanov, Boris, Liu, Simon, Li, Hui, Stoica, Bogdan A., Loane, David J., Faden, Alan I., Wu, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545988/
https://www.ncbi.nlm.nih.gov/pubmed/33052221
http://dx.doi.org/10.7150/thno.49199