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A snake toxin as a theranostic agent for the type 2 vasopressin receptor

Rationale: MQ1, a snake toxin which targets with high nanomolar affinity and absolute selectivity for the type 2 vasopressin receptor (V2R), is a drug candidate for renal diseases and a molecular probe for imaging cells or organs expressing V2R. Methods: MQ1's pharmacological properties were ch...

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Detalles Bibliográficos
Autores principales: Droctové, Laura, Lancien, Manon, Tran, Vu Long, Susset, Michaël, Jego, Benoit, Theodoro, Frederic, Kessler, Pascal, Mourier, Gilles, Robin, Philippe, Diarra, Sékou Siramakan, Palea, Stefano, Flahault, Adrien, Chorfa, Amélia, Corbani, Maithé, Llorens-Cortes, Catherine, Mouillac, Bernard, Mendre, Christiane, Pruvost, Alain, Servent, Denis, Truillet, Charles, Gilles, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545998/
https://www.ncbi.nlm.nih.gov/pubmed/33052234
http://dx.doi.org/10.7150/thno.47485