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A snake toxin as a theranostic agent for the type 2 vasopressin receptor
Rationale: MQ1, a snake toxin which targets with high nanomolar affinity and absolute selectivity for the type 2 vasopressin receptor (V2R), is a drug candidate for renal diseases and a molecular probe for imaging cells or organs expressing V2R. Methods: MQ1's pharmacological properties were ch...
Autores principales: | Droctové, Laura, Lancien, Manon, Tran, Vu Long, Susset, Michaël, Jego, Benoit, Theodoro, Frederic, Kessler, Pascal, Mourier, Gilles, Robin, Philippe, Diarra, Sékou Siramakan, Palea, Stefano, Flahault, Adrien, Chorfa, Amélia, Corbani, Maithé, Llorens-Cortes, Catherine, Mouillac, Bernard, Mendre, Christiane, Pruvost, Alain, Servent, Denis, Truillet, Charles, Gilles, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545998/ https://www.ncbi.nlm.nih.gov/pubmed/33052234 http://dx.doi.org/10.7150/thno.47485 |
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