BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway

Background: Bromodomain and extra-terminal domain (BET) inhibitors have shown profound efficacy against hematologic malignancies and solid tumors in preclinical studies. However, the underlying molecular mechanism in melanoma is not well understood. Here we identified secreted phosphoprotein 1 (SPP1...

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Detalles Bibliográficos
Autores principales: Deng, Guangtong, Zeng, Furong, Su, Juan, Zhao, Shuang, Hu, Rui, Zhu, Wu, Hu, Shuo, Chen, Xiang, Yin, Mingzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546000/
https://www.ncbi.nlm.nih.gov/pubmed/33052224
http://dx.doi.org/10.7150/thno.47432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546000/
https://www.ncbi.nlm.nih.gov/pubmed/33052224
http://dx.doi.org/10.7150/thno.47432

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