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Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress

Rationale: Tumors have significant abnormalities in various biological properties. In renal cell carcinoma (RCC), metabolic abnormalities are characteristic biological dysfunction that cannot be ignored. Despite this, many aspects of this dysfunction have not been fully explained. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Xiong, Zhiyong, Yuan, Changfei, shi, Jian, Xiong, Wei, Huang, Yu, Xiao, Wen, Yang, Hongmei, Chen, Ke, Zhang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546001/
https://www.ncbi.nlm.nih.gov/pubmed/33052225
http://dx.doi.org/10.7150/thno.48469