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Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress
Rationale: Tumors have significant abnormalities in various biological properties. In renal cell carcinoma (RCC), metabolic abnormalities are characteristic biological dysfunction that cannot be ignored. Despite this, many aspects of this dysfunction have not been fully explained. The purpose of thi...
Autores principales: | Xiong, Zhiyong, Yuan, Changfei, shi, Jian, Xiong, Wei, Huang, Yu, Xiao, Wen, Yang, Hongmei, Chen, Ke, Zhang, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546001/ https://www.ncbi.nlm.nih.gov/pubmed/33052225 http://dx.doi.org/10.7150/thno.48469 |
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