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Targeting BCL10 by small peptides for the treatment of B cell lymphoma

Rationale: Constitutive activation of the NF-κB signalling pathway plays a pivotal role in the pathogenesis of activated B cell-like diffuse large B-cell lymphomas (ABC-DLBCLs), the most aggressive and chemoresistant form of DLBCL. In ABC-DLBCLs, the CARMA1-BCL10 (CB) complex forms a filamentous str...

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Detalles Bibliográficos
Autores principales: Bao, Wei, Sun, Chenxia, Sun, Xiaochen, He, Miaoxia, Yu, Haolan, Yan, Wenfen, Wen, Fuping, Zhang, Liang, Yang, Chenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546004/
https://www.ncbi.nlm.nih.gov/pubmed/33052237
http://dx.doi.org/10.7150/thno.47533