Cargando…
Cardiomyocyte-derived small extracellular vesicles can signal eNOS activation in cardiac microvascular endothelial cells to protect against Ischemia/Reperfusion injury
Rationale: The crosstalk between cardiac microvascular endothelial cells (CMECs) and cardiomyocytes (CMs) has emerged as a key component in the development of, and protection against, cardiac diseases. For example, activation of endothelial nitric oxide synthase (eNOS) in CMECs, by therapeutic strat...
Autores principales: | Chen, Guihao, Xu, Chuansheng, Gillette, Thomas G., Huang, Tongyi, Huang, Peisen, Li, Qing, Li, Xiangdong, Li, Qinfeng, Ning, Yu, Tang, Ruijie, Huang, Cunrong, Xiong, Yuyan, Tian, Xiaqiu, Xu, Jun, Xu, Junyan, Chang, Liping, Wei, Cong, Jin, Chen, Hill, Joseph A., Yang, Yuejin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546010/ https://www.ncbi.nlm.nih.gov/pubmed/33052245 http://dx.doi.org/10.7150/thno.43163 |
Ejemplares similares
-
Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair
por: Xiong, Yuyan, et al.
Publicado: (2022) -
Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathway in high glucose-incubated human cardiac microvascular endothelial cells
por: Qi, Kang, et al.
Publicado: (2020) -
Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway
por: Xiong, Yuyan, et al.
Publicado: (2022) -
Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance
por: Huang, Peisen, et al.
Publicado: (2019) -
Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization by targeting microRNA-139-3p/Stat1 pathway
por: Ning, Yu, et al.
Publicado: (2023)