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Energy Landscape for the Membrane Fusion Pathway in Influenza A Hemagglutinin From Discrete Path Sampling
The conformational change associated with membrane fusion for Influenza A Hemagglutinin is investigated with a model based upon pre- and post-fusion structures of the HA2 component. We employ computational methods based on the potential energy landscape framework to obtain an initial path connecting...
Autores principales: | Burke, David F., Mantell, Rosemary G., Pitt, Catherine E., Wales, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546250/ https://www.ncbi.nlm.nih.gov/pubmed/33102445 http://dx.doi.org/10.3389/fchem.2020.575195 |
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