Non-Linear Mixed-Effects Pharmacokinetic Modeling of the Novel COX-2 Selective Inhibitor Vitacoxib in Cats

The objective of this study was to develop a non-linear mixed-effects (NLME) model to describe the disposition kinetics of vitacoxib in cats following intravenous (I.V) and oral (P.O) (single and multiple) dosing. Data from six consecutive studies with 16 healthy neutered domestic short hair cats we...

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Detalles Bibliográficos
Autores principales: Wang, Jianzhong, Schneider, Benjamin K., Xiao, Hongzhi, Qiu, Jicheng, Gong, Xiaohui, Seo, Yeon-Jung, Li, Jing, Mochel, Jonathan P., Cao, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546276/
https://www.ncbi.nlm.nih.gov/pubmed/33102567
http://dx.doi.org/10.3389/fvets.2020.554033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546276/
https://www.ncbi.nlm.nih.gov/pubmed/33102567
http://dx.doi.org/10.3389/fvets.2020.554033

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