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Leveraging Endogenous Dendritic Cells to Enhance the Therapeutic Efficacy of Adoptive T-Cell Therapy and Checkpoint Blockade

Adoptive cell therapy (ACT), based on treatment with autologous tumor infiltrating lymphocyte (TIL)-derived or genetically modified chimeric antigen receptor (CAR) T cells, has become a potentially curative therapy for subgroups of patients with melanoma and hematological malignancies. To further im...

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Detalles Bibliográficos
Autores principales: Hübbe, Mie Linder, Jæhger, Ditte Elisabeth, Andresen, Thomas Lars, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546347/
https://www.ncbi.nlm.nih.gov/pubmed/33101304
http://dx.doi.org/10.3389/fimmu.2020.578349