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Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor

Metaplastic breast carcinoma (MBC) is a clinically aggressive and rare subtype of breast cancer, with similar features to basal-like breast cancers. Due to rapid growth rates and characteristic heterogeneity, MBC is often unresponsive to standard chemotherapies; and novel targeted therapeutic discov...

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Detalles Bibliográficos
Autores principales: Chang, Tiffany C., Matossian, Margarite D., Elliott, Steven, Burks, Hope E., Sabol, Rachel A., Ucar, Deniz A., Wathieu, Henri, Zabaleta, Jovanny, Valle, Luis De, Gill, Sukhmani, Martin, Elizabeth, Riker, Adam I., Miele, Lucio, Bunnell, Bruce A., Burow, Matthew E., Collins-Burow, Bridgette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546483/
https://www.ncbi.nlm.nih.gov/pubmed/33035223
http://dx.doi.org/10.1371/journal.pone.0226464