Inferring a complete genotype-phenotype map from a small number of measured phenotypes

Understanding evolution requires detailed knowledge of genotype-phenotype maps; however, it can be a herculean task to measure every phenotype in a combinatorial map. We have developed a computational strategy to predict the missing phenotypes from an incomplete, combinatorial genotype-phenotype map...

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Detalles Bibliográficos
Autores principales: Sailer, Zachary R., Shafik, Sarah H., Summers, Robert L., Joule, Alex, Patterson-Robert, Alice, Martin, Rowena E., Harms, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546491/
https://www.ncbi.nlm.nih.gov/pubmed/32991585
http://dx.doi.org/10.1371/journal.pcbi.1008243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546491/
https://www.ncbi.nlm.nih.gov/pubmed/32991585
http://dx.doi.org/10.1371/journal.pcbi.1008243

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