Cargando…
Inferring a complete genotype-phenotype map from a small number of measured phenotypes
Understanding evolution requires detailed knowledge of genotype-phenotype maps; however, it can be a herculean task to measure every phenotype in a combinatorial map. We have developed a computational strategy to predict the missing phenotypes from an incomplete, combinatorial genotype-phenotype map...
Autores principales: | Sailer, Zachary R., Shafik, Sarah H., Summers, Robert L., Joule, Alex, Patterson-Robert, Alice, Martin, Rowena E., Harms, Michael J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546491/ https://www.ncbi.nlm.nih.gov/pubmed/32991585 http://dx.doi.org/10.1371/journal.pcbi.1008243 |
Ejemplares similares
-
Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps
por: Sailer, Zachary R., et al.
Publicado: (2017) -
First insights into the genotype–phenotype map of phenotypic stability in rye
por: Wang, Yu, et al.
Publicado: (2015) -
The architecture of an empirical genotype‐phenotype map
por: Aguilar‐Rodríguez, José, et al.
Publicado: (2018) -
On the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from Genotype
por: Dey, Gautam, et al.
Publicado: (2016) -
Elucidating the genotype–phenotype map by automatic enumeration and analysis of the phenotypic repertoire
por: Lomnitz, Jason G, et al.
Publicado: (2015)