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Endoplasmic reticulum visits highly active spines and prevents runaway potentiation of synapses

In hippocampal pyramidal cells, a small subset of dendritic spines contain endoplasmic reticulum (ER). In large spines, ER frequently forms a spine apparatus, while smaller spines contain just a single tubule of smooth ER. Here we show that the ER visits dendritic spines in a non-random manner, targ...

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Detalles Bibliográficos
Autores principales: Perez-Alvarez, Alberto, Yin, Shuting, Schulze, Christian, Hammer, John A., Wagner, Wolfgang, Oertner, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546627/
https://www.ncbi.nlm.nih.gov/pubmed/33033259
http://dx.doi.org/10.1038/s41467-020-18889-5