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Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery
Intercellular communication between tumor cells within the hypoxic microenvironment promote aggressiveness and poor patient prognoses for reasons that remain unclear. Here we show that hypoxic Ewing’s sarcoma (EWS) cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546758/ https://www.ncbi.nlm.nih.gov/pubmed/33088424 http://dx.doi.org/10.18632/oncotarget.27702 |