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Two Rationally Identified Novel Glitazones Reversed the Behavioral Dysfunctions and Exhibited Neuroprotection Through Ameliorating Brain Cytokines and Oxy-Radicals in ICV-LPS Neuroinflammatory Rat Model

The present study has planned to evaluate the neuroprotective activity of two novel glitazones in a neuroinflammatory rat model. Two novel glitazones were selected from an in-house virtual library of glitazones based on their docking scores against peroxisome proliferator-activated receptor-gamma (P...

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Detalles Bibliográficos
Autores principales: Justin, Antony, Ashwini, Premkumar, Jose, Jincy A., Jeyarani, Victoria, Dhanabal, S. P., Manisha, Chennu, Mandal, Subhankar P., Bhavimani, Guru, Prabitha, P., Yuvaraj, S., Prashantha Kumar, B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546828/
https://www.ncbi.nlm.nih.gov/pubmed/33100954
http://dx.doi.org/10.3389/fnins.2020.530148