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Synaptojanin2 Mutation Causes Progressive High-frequency Hearing Loss in Mice

Progressive hearing loss is very common in the human population but we know little about the underlying molecular mechanisms. Synaptojanin2 (Synj2) has been reported to be involved, as a mouse mutation led to a progressive increase in auditory thresholds with age. Synaptojanin2 is a phosphatidylinos...

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Detalles Bibliográficos
Autores principales: Martelletti, Elisa, Ingham, Neil J., Houston, Oliver, Pass, Johanna C., Chen, Jing, Marcotti, Walter, Steel, Karen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546894/
https://www.ncbi.nlm.nih.gov/pubmed/33100973
http://dx.doi.org/10.3389/fncel.2020.561857