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Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics

Acinetobacter baumannii is a Gram-negative bacterium primarily associated with hospital-acquired, often multidrug-resistant (MDR) infections. The ribosome-targeting antibiotics amikacin and tigecycline are among the limited arsenal of drugs available for treatment of such infections. We present high...

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Detalles Bibliográficos
Autores principales: Nicholson, David, Edwards, Thomas A., O'Neill, Alex J., Ranson, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546915/
https://www.ncbi.nlm.nih.gov/pubmed/32857965
http://dx.doi.org/10.1016/j.str.2020.08.004