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Severe delayed pulmonary toxicity following PD‐L1–specific CAR‐T cell therapy for non‐small cell lung cancer

OBJECTIVES: This phase I study aimed to evaluate the antitumor effect and safety of programmed death‐ligand‐1 (PD‐L1)–targeting autologous chimeric antigen receptor T (CAR‐T) cells for patients with non‐small cell lung cancer (NSCLC). METHODS: Programmed death‐ligand‐1–specific CAR‐T cells were gene...

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Detalles Bibliográficos
Autores principales: Liu, Heping, Ma, Yuxiang, Yang, Chaopin, Xia, Shangzhou, Pan, Qiuzhong, Zhao, Hongyun, Fang, Wenfeng, Chen, Xi, Zhang, Yang, Zou, Benyan, Li, Qiuyuan, Wan, Yang, Chen, Hao, Tang, Yan, Zhao, Jingjing, Weng, Desheng, Xia, Liming, Zhang, Li, Xia, Jianchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546952/
https://www.ncbi.nlm.nih.gov/pubmed/33072320
http://dx.doi.org/10.1002/cti2.1154