Cargando…
Severe delayed pulmonary toxicity following PD‐L1–specific CAR‐T cell therapy for non‐small cell lung cancer
OBJECTIVES: This phase I study aimed to evaluate the antitumor effect and safety of programmed death‐ligand‐1 (PD‐L1)–targeting autologous chimeric antigen receptor T (CAR‐T) cells for patients with non‐small cell lung cancer (NSCLC). METHODS: Programmed death‐ligand‐1–specific CAR‐T cells were gene...
Autores principales: | Liu, Heping, Ma, Yuxiang, Yang, Chaopin, Xia, Shangzhou, Pan, Qiuzhong, Zhao, Hongyun, Fang, Wenfeng, Chen, Xi, Zhang, Yang, Zou, Benyan, Li, Qiuyuan, Wan, Yang, Chen, Hao, Tang, Yan, Zhao, Jingjing, Weng, Desheng, Xia, Liming, Zhang, Li, Xia, Jianchuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546952/ https://www.ncbi.nlm.nih.gov/pubmed/33072320 http://dx.doi.org/10.1002/cti2.1154 |
Ejemplares similares
-
Adjuvant alternative cytokine-induced killer cell combined with natural killer cell immunotherapy improves the prognosis of post-mastectomy breast cancer
por: Yang, Xinyi, et al.
Publicado: (2022) -
Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma
por: Yang, Chaopin, et al.
Publicado: (2023) -
Lenvatinib improves anti-PD-1 therapeutic efficacy by promoting vascular normalization via the NRP-1-PDGFRβ complex in hepatocellular carcinoma
por: Yang, Jieying, et al.
Publicado: (2023) -
SPC25 promotes proliferation and stemness of hepatocellular carcinoma cells via the DNA-PK/AKT/Notch1 signaling pathway
por: Yang, Jieying, et al.
Publicado: (2022) -
Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin
por: Sun, Fengze, et al.
Publicado: (2021)