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The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis

Dysregulated RNA metabolism is emerging as a crucially important mechanism underpinning the pathogenesis of frontotemporal dementia (FTD) and the clinically, genetically and pathologically overlapping disorder of amyotrophic lateral sclerosis (ALS). Heterogeneous nuclear ribonucleoproteins (hnRNPs)...

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Detalles Bibliográficos
Autores principales: Bampton, Alexander, Gittings, Lauren M., Fratta, Pietro, Lashley, Tammaryn, Gatt, Ariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547044/
https://www.ncbi.nlm.nih.gov/pubmed/32748079
http://dx.doi.org/10.1007/s00401-020-02203-0