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Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

Many intestinal pathogens, including Clostridioides difficile, use mucus-derived sugars as crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are therefore ecological gatekeepers in healthy guts, and are attractive candidates for therapeutic interventions. Nevert...

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Detalles Bibliográficos
Autores principales: Pereira, Fátima C., Wasmund, Kenneth, Cobankovic, Iva, Jehmlich, Nico, Herbold, Craig W., Lee, Kang Soo, Sziranyi, Barbara, Vesely, Cornelia, Decker, Thomas, Stocker, Roman, Warth, Benedikt, von Bergen, Martin, Wagner, Michael, Berry, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547075/
https://www.ncbi.nlm.nih.gov/pubmed/33037214
http://dx.doi.org/10.1038/s41467-020-18928-1