Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy

Mitochondrial ClpP is a serine protease located in the mitochondrial matrix. This protease participates in mitochondrial protein quality control by degrading misfolded or damaged proteins, thus maintaining normal metabolic function. Mitochondrial ClpP is a stable heptamer ring with peptidase activit...

Descripción completa

Detalles Bibliográficos
Autores principales: Nouri, Kazem, Feng, Yue, Schimmer, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547079/
https://www.ncbi.nlm.nih.gov/pubmed/33037181
http://dx.doi.org/10.1038/s41419-020-03062-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547079/
https://www.ncbi.nlm.nih.gov/pubmed/33037181
http://dx.doi.org/10.1038/s41419-020-03062-z

Ejemplares similares