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An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility

Nucleosome turnover concomitant with incorporation of the replication-independent histone variant H3.3 is a hallmark of regulatory regions in the animal genome. Nucleosome turnover is known to be universally linked to DNA accessibility and histone acetylation. In mouse embryonic stem cells, H3.3 is...

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Detalles Bibliográficos
Autores principales: Navarro, Carmen, Lyu, Jing, Katsori, Anna-Maria, Caridha, Rozina, Elsässer, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547087/
https://www.ncbi.nlm.nih.gov/pubmed/33037201
http://dx.doi.org/10.1038/s41467-020-18863-1