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The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice

Myocardial inflammation has recently been recognized as a distinct feature of cardiac hypertrophy and heart failure. HectD3, a HECT domain containing E3 ubiquitin ligase has previously been investigated in the host defense against infections as well as neuroinflammation; its cardiac function however...

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Detalles Bibliográficos
Autores principales: Rangrez, Ashraf Yusuf, Borlepawar, Ankush, Schmiedel, Nesrin, Deshpande, Anushka, Remes, Anca, Kumari, Manju, Bernt, Alexander, Christen, Lynn, Helbig, Andreas, Jungmann, Andreas, Sossalla, Samuel, Tholey, Andreas, Müller, Oliver J., Frank, Derk, Frey, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547098/
https://www.ncbi.nlm.nih.gov/pubmed/33037313
http://dx.doi.org/10.1038/s42003-020-01289-2