Biomimetic Synthesis and Evaluation of Interconnected Bimodal Mesostructured MSF@Poly(Ethyleneimine)s for Improved Drug Loading and Oral Adsorption of the Poorly Water-Soluble Drug, Ibuprofen

PURPOSE: The aim of this study was to improve the oral bioavailability and anti-inflammatory activity of the poorly soluble drug ibuprofen (IBU) by employing a new kind of poly(ethyleneimine)s (PEIs)-based mesocellular siliceous foam (MSF) called B-BMSF@PEI as drug carrier. METHODS: B-BMSF@PEI was b...

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Detalles Bibliográficos
Autores principales: Xin, Wei, Wang, Yumei, Guo, Xianmou, Gou, Kaijun, Li, Jing, Li, Sanming, Zhao, Lin, Li, Heran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547139/
https://www.ncbi.nlm.nih.gov/pubmed/33116481
http://dx.doi.org/10.2147/IJN.S272796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547139/
https://www.ncbi.nlm.nih.gov/pubmed/33116481
http://dx.doi.org/10.2147/IJN.S272796

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