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Biomimetic Synthesis and Evaluation of Interconnected Bimodal Mesostructured MSF@Poly(Ethyleneimine)s for Improved Drug Loading and Oral Adsorption of the Poorly Water-Soluble Drug, Ibuprofen
PURPOSE: The aim of this study was to improve the oral bioavailability and anti-inflammatory activity of the poorly soluble drug ibuprofen (IBU) by employing a new kind of poly(ethyleneimine)s (PEIs)-based mesocellular siliceous foam (MSF) called B-BMSF@PEI as drug carrier. METHODS: B-BMSF@PEI was b...
Autores principales: | Xin, Wei, Wang, Yumei, Guo, Xianmou, Gou, Kaijun, Li, Jing, Li, Sanming, Zhao, Lin, Li, Heran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547139/ https://www.ncbi.nlm.nih.gov/pubmed/33116481 http://dx.doi.org/10.2147/IJN.S272796 |
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