Transient Receptor Potential Canonical 4 and 5 Channel Antagonist ML204 Depolarized Pacemaker Potentials of Interstitial Cells of Cajal

BACKGROUND/AIMS: To investigate an effect of ML204 (an inhibitor of transient receptor potential canonical 4 and 5 [TRPC4/5] channels) on interstitial cells of Cajal (ICCs) and therefore determine whether TRPC4/5 channels act on ICC-generated pacemaker activity. METHODS: We enforced whole cell patch...

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Detalles Bibliográficos
Autores principales: Lee, Jun Hyung, Wu, Wen-Hao, Huang, Xing-You, Jun, Jae Yeoul, Choi, Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Neurogastroenterology and Motility 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547197/
https://www.ncbi.nlm.nih.gov/pubmed/32321198
http://dx.doi.org/10.5056/jnm20064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547197/
https://www.ncbi.nlm.nih.gov/pubmed/32321198
http://dx.doi.org/10.5056/jnm20064

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