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Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer

Targeted treatments for advanced gastric cancer (GC) are needed, particularly for HER2-negative GC, which represents the majority of cases (80 to 88%). In this study, in silico analyses of the lysine histone demethylases (KDMs) involved in diverse biological processes and diseases revealed that PHD...

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Detalles Bibliográficos
Autores principales: Tseng, Lin-Lu, Cheng, Hsin-Hung, Yeh, Ta-Sen, Huang, Shih-Chiang, Syu, Ya-Yun, Chuu, Chih-Pin, Yuh, Chiou-Hwa, Kung, Hsing-Jien, Wang, Wen-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547212/
https://www.ncbi.nlm.nih.gov/pubmed/32958674
http://dx.doi.org/10.1073/pnas.1919766117