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Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer
Targeted treatments for advanced gastric cancer (GC) are needed, particularly for HER2-negative GC, which represents the majority of cases (80 to 88%). In this study, in silico analyses of the lysine histone demethylases (KDMs) involved in diverse biological processes and diseases revealed that PHD...
Autores principales: | Tseng, Lin-Lu, Cheng, Hsin-Hung, Yeh, Ta-Sen, Huang, Shih-Chiang, Syu, Ya-Yun, Chuu, Chih-Pin, Yuh, Chiou-Hwa, Kung, Hsing-Jien, Wang, Wen-Ching |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547212/ https://www.ncbi.nlm.nih.gov/pubmed/32958674 http://dx.doi.org/10.1073/pnas.1919766117 |
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