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Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is hypothesized to be driven by an overreacting innate immune response, where the complement system is a key player. In this prospective cohort study of 39 hospitalized coronavirus disease COVID-19 patients, we...

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Detalles Bibliográficos
Autores principales: Holter, Jan C., Pischke, Soeren E., de Boer, Eline, Lind, Andreas, Jenum, Synne, Holten, Aleksander R., Tonby, Kristian, Barratt-Due, Andreas, Sokolova, Marina, Schjalm, Camilla, Chaban, Viktoriia, Kolderup, Anette, Tran, Trung, Tollefsrud Gjølberg, Torleif, Skeie, Linda G., Hesstvedt, Liv, Ormåsen, Vidar, Fevang, Børre, Austad, Cathrine, Müller, Karl Erik, Fladeby, Cathrine, Holberg-Petersen, Mona, Halvorsen, Bente, Müller, Fredrik, Aukrust, Pål, Dudman, Susanne, Ueland, Thor, Andersen, Jan Terje, Lund-Johansen, Fridtjof, Heggelund, Lars, Dyrhol-Riise, Anne M., Mollnes, Tom E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547220/
https://www.ncbi.nlm.nih.gov/pubmed/32943538
http://dx.doi.org/10.1073/pnas.2010540117